Description Description Nandrolone Phenylpropionate (NPP) is an anabolic androgenic steroid (AAS), derived from testosterone. It is a short-ester variant of nandrolone, differing from Nandrolone Decanoate (Deca-Durabolin) mainly in the ester, which affects how quickly it is released into the bloodstream. It is typically found in 100 mg/ml injectable form. Chemical Name: 19-nortestosterone phenylpropionate Molecular Formula: C27H34O3 Anabolic:Androgenic Ratio: ~125:37 Half-life: ~2–4 days Detection Time: ~12 months 2. Medical & Performance Usage Medical Use NPP has been used clinically for: Treatment of muscle wasting diseases Anemia Osteoporosis Severe burns Hormonal therapy (off-label in some cases) Performance/Bodybuilding Use (Note: non-medical use may be illegal depending on jurisdiction) Muscle growth (lean mass) Increased strength Enhanced recovery Joint relief (due to increased synovial fluid retention) 3. Dosage & Administration Medical Dosage Varies depending on condition: typically 50–100 mg every 3–4 days. Bodybuilding Dosage (for informational purposes only) Men: 100–200 mg every other day or 300–600 mg/week, split into multiple injections due to short half-life. Women: 25–50 mg/week (though risk of virilization is high, and use is generally discouraged). Route of Administration: Intramuscular injectionFrequency: Due to the phenylpropionate ester, injections are commonly done every other day or 3x per week. 4. Side Effects Androgenic Effects Acne Hair loss (in genetically predisposed individuals) Increased body/facial hair Deepening of the voice (especially in females) Estrogenic Effects (via aromatization to estradiol) Water retention Gynecomastia Elevated blood pressure (These can be mitigated with an aromatase inhibitor) Other Possible Effects Suppression of natural testosterone production Altered cholesterol levels (reduced HDL, increased LDL) Liver toxicity (minimal as it’s not 17-alpha alkylated) Aggression or mood swings In Females High virilization risk: voice changes, clitoral enlargement, body hair growth, menstrual irregularities 5. Pharmacokinetics Absorption: Rapid after intramuscular injection due to the short ester Onset of Action: Within 24–48 hours Half-life: Approximately 2–4 days Peak Levels: ~24–48 hours post-injection Metabolism: Primarily in the liver, via reduction and conjugation Excretion: Renal (urine) Important Notes PCT (Post Cycle Therapy) is recommended after discontinuing use to restore natural testosterone production. Not approved for over-the-counter use; typically prescription-only in countries where legal. WADA-banned substance: Not allowed in competitive sports.
